THE NATURAL LAWS OF THE VIRTUAL ENERGY KEEP ON EXCERCISING ALL OVER THE UNIVERSE IN NON-LIVINGS AND LIVINGS BOTH. IN NON-LIVINGS THIS ENERGY EXPRESSION HAS BEEN BROADLY DEFINED IN ‘BIHARI-SIR’ SCIENCE & TECHNOLOGY, WHICH IS SIMILARLY REPRESENTED IN TRIANGLE AS DEPICTED ABOVE.

IN THE LIVING IDENTITIES NUCLEAR DIVISION IS BURNING EXAMPLE OF BIO-ENERGY AUGMENTAION AND PROLIFERATION. IN THE PROCESS OF CELL DIVISION (SEE ABOVE NOTED ENERGY TRIANGLES) NPS & SECOND MESSENGER PLAY AS ENERGY AUGMENTED MOTIVE FORCE IN ASSISTANCE WITH CENTRIOLE AND MITOCHONDRIAL ACTIVATION. THE ACTIVITIES OF THE NUCLEUS PER SE REPRESENT EXPRESSION OF THE VIRTUAL ENERGY AUGMETATION.

  ACCORDING TO THE AUTOPATHY DICTUM OF THOUGHTS DISEASES CAN BE ATTACKED BY COMMANDING ON THE ACTIVITIES OF CENTROSOMAL & CHROMOSOMAL HOUSINGS OF THE CYTOLOGICAL CONTROL BEING GOVERNED BY NUCLEOLUS.THE NUCLEUS IS THE SITE FOR ENERGY AUGMENTATION EXPRESSED AS VIRTUAL ENERGY, AND THE NUCLEOLUS THEREBY PROVIDES MOTIVE FORCE GOVERNING ELEMENTS INDUCING THE PROCESS OF CELL DIVISION.   

  THE HUMAN BODY IS MADE UP OF CELLS AND OF INTRACELLULAR SUBSTANCES PRODUCED BY THE CELLS. MANY CELLS OF THE BODY HAVE A LIMITED SPAN OF FUNCTIONAL ACTIVITIES AT THE END OF WHICH THEY UNDERGO DIVISION INTO TWO DAUGHTER CELLS. THE PERIOD BETWEEN TWO SUCCESSIVE CELL DIVISIONS IS CALLED INTERPHASE.DURING THIS PERIOD MATURATION OF THE CELLS TAKES PLACE.A MATURED CELL GETS ARRANGED ALL THE REQUIREMENTS FOR ITS NUCLEAR PROLIFERATION OR CELL DIVISION. DURING CELL DIVISION TREMENDOUS QUANTUM OF BIO-ENERGY AUGMENTATION IS NEEDED WHICH IS ENSURED BY HIGHLY ACTIVATED MATERNAL MITOCHONDRIAS. DURING CELL DIVISION NUMEROUS CHANGES OCCURE IN THE CHROMOSOMES. WHILE THESE CHANGES ARE OCCURRING A NUMBER OF OTHER EVENTS ALSO TAKES PLACE INSIDE THE CELL. MATURED NORMAL CELL, SURROUNDED BY ADDITIONAL REPLICATING MATERIALS FILLED INTRACELLULAR SPACE, IS SUBJECTED TO STRONG EXTRACELLULAR ‘NUCLEAR PROLIFERATIVE STIMULI’ (NPS). THESE STIMULI PROVOCATE SECOND MESSENGER INSIDE THE ‘EXTRANUCLEAR AREA’ OF THE CELL. THE SECOND MESSENGER ACTIVATES NUCLEOLUS RESIDING INSIDE THE ‘INTRANUCLEAR AREA’ TO ASSESS THE PREPAREDNESS OF THE CELL WITH REPLICATIVE STRUCTURAL MATERIALS. HAVING FOUND ITS SATISFACTORY QUANTUM THE NUCLEOLUS GIVES COMMAND TO THE CENTROSOMAL SYSTEM AND TO THE MITOCHONDRIAL ARRANGEMENTS TO GO AHEAD WITH THE CELL DIVISION PROCESS. AND THE NUCLEOLUS DISAPPEARS FROM THE SITE. THE SECOND MESSENGER ENGINEERS WHOLE PROCESS OF THE CELL DIVISION USING EXTRA CELLULAR, INTRACELLULAR AND INTRANUCLEAR RESOURCES ON EXPENSE OF AUGMENTED MITOCHONDRIAL ENERGY DISTRIBUTION AS SHOWN IN THE BIO-ENERGY TRIANGLES–[1]. EFFECTS OF THIS AUGMENTED BIO-ENERGY EXPRESSION MAY BE SUMMARIZED AS UNDER.THE TWO CENTRIOLES SEPARATE AND MOVE TO OPPOSITE POLES OF THE CELL. THE NUCLEAR MEMBRANE BREAKS DOWN AND NUCLEOLUS DISAPPEARS. AT THE END OF THE CELL DIVISION THE NUCLEOLUS REAPPEARS. THE CENTRIOLE IS NOW DUPLICATED AT THIS STAGE OR IN EARLY INTERPHASE. IN THIS PROCESS THE ORGANELLS ARE ALSO DUPLICATED AND EACH DAUGHTER CELL COMES TO HAVE FULL COMPLEMENTS OF THEM.THE INTERPHASE PROCEEDS AGAIN FOR THE CELL MATURATION.

MANY HUMAN NEOPLAMS ARE ASSOCIATED WITH NONRANDOM CHROMOSOMAL ABNORMALTIES, SUGGESTING THAT CERTAIN CYTOGENIC ABNORMALTIES MUST BE IMPORTANT AND PRIMARY EVENT IN NEOPLASTIC TRANSFORMATION. BASED ON LITERATURE, OWN EXPERIMENTAL AND CLINICAL EXPERIENCE IT HAS BEEN CONCEIVED THAT PATERNAL MITOCHONDRIAS PRESENT IN SIDE THE EXTRANUCLEAR SPACE OF A CELL ARE SUBJECTED TO GENE AMPLIFICATION.THESE MUTANT MITOCHONDRIAS PLAY AS PRIMARY/ BASIC EVENT IN NEOPLASTIC TRANSFORMATION. ‘NUCLEAR PROLIFERATIVE STRONG STIMULI’ (NPS) ON THE CELL MEMBRANE OF A PROSPECTIVE CELL ARE PROTESTED AT ITS PRIMARY SITE IN TWO MODES: BY DISPLASIA AND ANAPLASIA. THE FIRST SUCH MANIFESTATION IS PREDECESSOR OF THE SECOND. IF THE STIMULI PROVOCATING MATERIALS ARE NOT ELIMINATED BY DISPLASIA THE PROCESS OF ANAPLASIA DEVELOPS AS ULTIMATE TOOL OF DEFENCE. THIS IS EXPRESSED AS GENE AMPLIFICATION [ON THE COST OF AUGMENTED BIO-ENERGY] IN THE PATERNAL MITOCHONDRIAS (MMS), AND PLEOMORPHISM CAUSED BY THE SECOND MESSENGER (SMS). IN THE NEXT GENERATION OF THE ANAPLASTIC CELLS THE DUTIES OF THE NUCLEAR PROLIFERATIVE STIMULI & SECOND MESSENGER BOTH ARE PERFORMED BY THESE PATERNAL MUTANT MITOCHONDRIAS (MMS); WHICH TOO GET REPLICATED AND TRANSFERRED TO THE DAUGHTER CELLS CAUSING GENERATION OF ADDITIONAL CENTRIOLE (ACL) SPINDLES WITHOUT DISAPPEARANCE OF THE NUCLEOLI (NLA). THEY TOO LOOK PROMINENT [DUETO AUGMENTED ENERGY ACCUMULATION] IN THE PLEOMORPHIC NEOPLASTIC CELLS. THE SURROUNDING DISPLASTIC CELLS AT THE PRIMARY SITE OF EVENTS KEEP ON MANUFACTURING & SUPPLYING REPLICATION STRUCTURAL MATERIALS FOR UNINTERRUPTED NEOPLASTIC CELL DIVISION. OTHER BASIC FEATURES OF THE NEOPLASTIC CELL DIVISION SCARCELY DIFFER FROM NORMAL CELL DIVISION EXCEPT THOSE GENETICAL TRANSFORMATIONAL OUT-PUTS RELATED TO ACTIVATED AND BALANCED TRANSLOCATION, DELETION OF CHROMOSOMES AND MANY OTHER GENES AMPLIFICATION.THIS EVENT OF MUTANT PATERNAL MITOCHONDRIAS’ (MMS) REPLICATION IS EXPRESSED AS LOCAL IGNORANCE OF DEFENCE MECHANISM IN CASE OF CANCER/NEOPLASTIC GROWTH.WHEREAS, SUCH MUTATION IN MATERNAL MITOCHONDRIAS (MMM) LEADS TO GENERALISED IGNORANCE OF DEFENCE MECHANISM, AS IT HAPPENS IN CASE OF AIDS. BIO-ENERGY AUGMENTATION ACTION MECHANISM IN NEOPLASTIC CELL DIVISION HAS BEEN SHOWN IN THE BIO-ENERGY TRIANGLES – [2].

SIMILARLY, DURING GESTATION PERIOD TREMENDOUS BIOENERGY AUGMENTATION HELPS DEVELOPING GASTRULA TO EMBROY, AND EMBROY TO FEOTUS.